Immunogenetic Aspects Of Pathogenesis Of Chronic Hcv-Infection (Review)

Khamid Karimov, Sevara Azimova, Bakhtiyor Iriskulov


Viral hepatitis B and C is a relevant issue because of high prevalence and degree of chronicity, late diagnosis and poor prognosis. Today, protein products of numerous genes are involved in the pathogenesis of viral pathology of the liver. In this review, the authors analyzed 42 literature sources on genetic basis of susceptibility to various infectious diseases. Study of the role of immunogenetic factors is of great practical importance to develop methods for predicting outcomes of viral hepatitis.


Chronic Hepatitis B And C, HCV-Infection, Pathogenesis, Immunogenetic Factors, CTLA-4 Gene

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