Syndromes Of Intracavitary And Intraorgan Hypertension In Surgical Practice

V Timerbulatov, Sh Timerbulatov


Background: Pathological conditions caused by intraorgan and intracavitary hypertension have shown to be common in medical practice. Syndromes of intraabdominal, intracranial hypertension in limb fracture cases are most thoroughly studied and best characterized. Nevertheless, the significance of the above syndromes to the entire body has not been efficiently defined.

Methods: The implication of excessive pressure has been studied by direct and indirect measuring of pressure inside organs and body cavities in cases of brain injury, lung disease, and various conditions of abdominal cavity organs, including severe abdominal pathologies and traumas, injuries to the limbs.

Results: Interorgan, intracavitary and intertissular hypertension syndromes were found to be characterised by polyetiologic nature, similar pathogenesis mechanisms and accompanied by organ dysfunction or multiorgan insufficiency, based on examination data obtained from 1955 patients, including 70 craniocerebral injury patients, 296 severe abdominal pathology patients, 316 pulmonary pathology patients, 336 Mallory-Weiss syndrome patients, 524 complicated diverticular colon disease patients, 213 acute intestinal obstruction patients, 200 severe shin-bone fracture patients.

Conclusion: Interorgan, intracavitary and intertissular hypertension syndromes can be defined as a uniform (model)  pathological process caused by traumatic, infectious, metabolic, vascular factors and conditioned by a disparity between the contents volume and the volume-capacity of the organ cavity, increased pressure inside of them (>10mm Hg) and a pronounces disturbance in interorgan and intertissular perfusion. The authors consider intracavitary, interorgan and intertissular pressure of ≤10 mm Hg to be accepted as the constant value for a human body.

Full Text:



Girshin S.G. Clinical Practice-Based Lectures on Emergency Traumatology. – Moscow: 2004: 280-184.

Grushevski V.Ye. The foundations of Clinical Hydrostasiology. – Krasnoyarsk: 2008. – 504 p.

Gulyayev A.A., Shapovalyants S.G., Burova V.A. Lumen Obliteration of the Gall-Bladder in High Surgical Risk Patients // Surgery 1998; 9: 35-42.

Ivanov V.I. Acute Intratissular Hypertension (Compartment) Syndrome in Closed Injuries to Lower Extremities in Patients with Concomitant and Multiple Traumas: Author’s Abstract of Doctoral Thesis in Medical Science. –Rostov-na-Donu: 2005. – 24 p.

Ivanov V.I., Tatyanchenko V.K., Yelfimov A.L. Mean Values Estimation of Intratissular Hypertension in Healthy Individuals //Russian Federation National Congress “Humans and Their Health”: Congress Materials. – St.Petersburg: 2005: 44.

Ivanov V.I., Laka A.A., Ivanov D.V. Anatomical Preconditions of Intratissular Hypertension Syndrome, Compartment Syndrome in Lower Leg // Third International Congress “Current Technologies on Traumatology and Orthpedics”: Congress Proceedings. – Peoples’ Friendship University of Russia, Moscow: 2006: 339.

Kaplan A.V. Injuries to Bones and Joints. – Moscow: Medicine, 1979: 568.

Maslyakov V.V., Sobolev V.I., Dzhanshanov D.I. Immediate and Long-term Results of Heart Injury Treatment // Surgical Annals 2009; 2:28-30.

Nazarenko G.I., Konuchevski A.B., Minasyan A.M. Compartment Syndrome in Patients with Surgical Pathologies // Priorov N.N. Journal of Traumatology and Othopedics 1999; 3:3-11.

Nechayev E.A., Rayevski A.K., Savitski G.G. Syndrome of Long-Term Compression (Manual for Doctors). – Moscow: 1993. – 365 p.

Strafun S.S. Prevention and Treatment of Ischaemic Wrist Contracture: Author’s Abstract of Candidate’s Thesis in Medical Science. –Kiev: 1991. – 22 p.

Timerbulatov V.M. Diagnosis and Treatment of Colon Diverticulosis and its Complications (Substanciation and Treatment Modality Choice): Author’s Abstract of Canidate’s Thesis in Medical Science. –Moscow: 1983. – 18 p.

Timerbulatov V.M., Kalanov R.G., Plechev V.V. Colonic Obstruction (Diagnosis, Treatment, reabilitation). – Ufa: Bashkortostan State Medical University Publishing House, 1999. -164p.

Timerbulatov V.M., Sakhautdinov V.G., Mekhdiyev D.I. Diverticular Colon Disease. – Moscow: Triada-X, 2000. – 192p.

Timerbulatov V.M., Kunafin M.S., Fayazov R.R. Modern Approaches to Compartment Syndrome Management in Abdominal Surgery // Bashkortostan Medical Bulletin 2007; 2: 110-113.

Timerbulatov V.M., Timerbulatov Sh.V. Abdominal Ischemia Syndrome // Complications Prevention in Gastrointestinal Tract Reconstructive Surgery. – Ufa-Moscow: 2008: 44-62.

Timerbulatov V.M., Fayazov R.R., Timerbulatov Sh.V. Intraabdominal Pressure in Acute Obstruction of Colon // Surgical Annals 2008; 5: 36-38.

Timerbulatov V.M., Fayazov R.R., Timerbulatov Sh.V. Intracavitary Hypertension Syndrome in Surgical Clinical Practice // Bulletin of the Russian Academy of Sciences 2009; 2: 10-12.

Timerbulatov Sh.V., Timerbulatov V.M., Khasanov A.G. Specifications of Treatment Tactics in Mallory-Weiss Syndrome // Surgery 2009; 4: 33-37.

Cherepanin A.I.. Mikayelyan I.A. Evolution of Surgery for the Treatment of Acute Cholecystitis // Surgeon 2009; 5: 67-75.

Chereshnev V.A., Davydov V.V. Pathology. – Moscow, GEOTAR-Media, 2009: 1. – 608 p.

Shapkin Yu.G., Mukhina V.M. Outcomes of Surgical Treatment in Heart Injuries // Surgical Annals 2008; 1: 33-34.

Shishkov V.P., Zharov A.V., Zhakov A.S. Pathological Anatomy of Livestock Animals. Fourth edition, adapted and revised. – Moscow, Kolos, 2001. – 568 p.

Bradley S.E., Bradley G.P. The Effect of Intra-Abdominal Pressure on Renal Function in Man // J.Clin.Invest.1947; 26: 1010-1022.

Cheatham M.L. Intra-Abdominal Hyperstension and Abdominal Compartment Syndrome // New Horiz.1999; 7: 96-l 15.

Cheatham M.L., Malbrain M.L.N.G. Abdominal Perfusion Pressure. Abdominal Compartment Syndrome // Landes Bioscience / Eds. R. Ivatury, M. Malbrain, M. Surgue. - Georgetown, 2006: 69-81.

Cheatham M.L. Abdominal Perfusion Pressure: a Superior Parameter in the Assessmeht of Intra-Abdominal Hyperstension // J.Trauma 2000; 4. - V.49: 621-626.

Coombs H.C. The Mechanism of Regulation of Intra-Abdominal Pressure //Am.J.Physiol. 1922; 61: 159.

Czosnyka М., Pickard J.D. Monitoring and Interpretation of Intracranial Pressure //J.Neurol. Neurosurg Psychiatry 2004; 75: 813-821.

Eitan A., Toledano C, Rivlin E. Early vs. Delayed Cholecystectomy for Acute Cholecystitis // Harefuah 1991; 6.- Vol. 120: 319-323.

Gray W.J., Rosher M.J. Pressure - Volume Index as a Function of Cerebral Perfusion Pressure. Part 2: The Effects of Low Cerebral Perfusion Pressure and Autoregulation // J.Neurosurg l987; 67: 377-380.

Malbrain M.L.N.G. Abdominal Pressure in the Critically Ill // Curr.Opin.Crit.Care 2000; 6: 17-29.

Malbrain M.L.N.G. Abdominal Perfusion Pressure as a Prognostic Marker in Intra-Abdominal Hypertension // Yearbook of Intensive Care and Emergency Medicine / J.L.Vincent. - New-York-Berlin-Heidelberg, 2002: 792-814.

Mallory G.K., Weiss S. Hemorrhage from Laseration of the Cardiac Orifice of the Stomach due to Vomiting // Am.J.Med.Sci. 1929; 178: 506-515.

Mazzola С A., Adelson P.D. Critical Care Management of Head Trauma in Children // Crit.Care.Med. 2002; 30: 393-401.

Мс Queen M.M. The Epidemiology and Outcome of Acute Compartment Syndrome. Das Compartment-Syndrom. - Berlin- Heidelberg-New York: Springer-Verlay, 1998: 14-15.

Moehring H.D., Voigtlander J.P. Compartment Pressure Monitoring During Intramedullary Fixation of Tibial Fractures // Orthopedics 1995; 7. – V. l8: 631-635.

Mubarack S.J., Owen C.A., Hargens A.R. Acute Compartment Syndromes: Diagnosis and Treatment with the Aid of the Wickatheter // J.Bone JT.Surg.1978 [Am]; 60-A:1091-1095.

0verholt R.H. Intraperitoneal Pressure // Arch.Surg.1931; 22: 691-703.

Rosner M.J., Rosner S.D., Johnson A.H. Cerebral Perfusion Pressure Management Protocol and Clinical Resurlts // J.Neurosarg1995; 83: 949-962.



  • There are currently no refbacks.

Print ISSN 1804-5804, Online ISSN 1804-9702

(c) 2018 CBU,o.p.s.