Yuliya Modna, Tatiana Tananakina, Elina Dyka, Ievgen Mozhaiev, Pavlo Borodin


The acute destructive pneumonias (ADP) occupy up to 80% of the total number of pneumonias. They require constant improvement of treatment strategy. Nowadays the use of surfactants is a part of most treatment protocols. The aim was to study the features of the solid phase bronchoalveolar lavage in children with the ADPs in the dynamics of complex treatment with exogenous surfactant.

Material and methods: We examined 39 patients of contaminated surgery. We identified 2 groups of patients. The patients of first group (n=27) had pulmonary pleural form of ADP, the second group (n=12) had pulmonary form of ADP. All patients got classical treatment and the earlier draining of pleural cavity. We used as an antiseptic reamberin 1.5% by 10 ml/kg and endobronchially injected exogenous surfactant Bl in dose12 mg/kg body weight a day, 6 mg/kg every 12 hours. All the children were made a bronchoscopy to obtain BAL to study the crystallization properties. The solid phase of BAL was studied by method of cuneal dehydration.

Results: All facies before treatment were divided into two groups according to classification of facies of biological fluids. Only the facies of the second and the third types were detected there. It was revealed that the sizes of the zones of the facies were different in the comparison groups before treatment and after. And the level of crystalline structures and amorphous aggregates were different in the groups with different degrees of inflammation.

Conclusion: So, we can assume that the change in surfactant system is characterized by changes in the morphological structure of solids phases of BAL. And the morphological structure of BAL depends on the chemical composition of BAL.


Bronchoalveolar Lavages, Cuneal Dehydration, Lung Surfucant System

Full Text:



Michelow, I.C., Olsen, K., Lozano, J., Rollins, N.K., Duffy, L.B., Ziegler, T., Kauppila, J.,Leinonen, M. and McCracken, G.H. (2004). Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children. Journal of Pediatrics, 4, 701–707.

Wexler, I.D., Knoll, S., Picard, E., Villa, Y., Shoseyov, D., Engelhard, D. and Kerem, E. (2006). Clinical characteristics and outcome of complicated pneumococcal pneumonia in a pediatric population. Pediatric Pulmonoly, 8, 726-734.

Sahs, S.A. (2007). Diagnosis and management of parapneumonic effusions and empyema. Clinical Infectious Diseases, 11, 1480-1486.

Hacimustafaoglu, M., Colobi, S., Sarimehmel, H., Gurpinar, A. and Ercan, I. (2004). Necrotizing pneumonia in children. Acta Paediatrica, 93, 1172-1177.

Сhotigeat, U., Promwong, N., Kanjanapattanakul, W., Khorana, M., Sangtawesin, V. and Horpaopan, S.J. (2008). Comparison outcomes of surfactant therapy in respiratory distress syndrome in two periods. Journal of the Medical Association of Thailand, 3, 109-114

Picinin, I.F., Camargos, P.A. and Marguet, C. (2010). Cell profile of BAL fluid in children and adolescents with and without lung disease. Jornal Brasileiro de Pneumologia, 3, 372-385.

Tarasevich, Yu.Yu. and Ayupova, A.K. (2003) Vlijanie diffusii na razdelenie komponentov biologicheskoy shidkosti pri klinovidnoy [The influence of diffusion on the separation of the components of biological fluids for dehydration wedge]. Technical Physics, 5, 13-18.



  • There are currently no refbacks.

Print ISSN 1804-5804, Online ISSN 1804-9702

(c) 2018 CBU,o.p.s.