Bulent Aytac, Ahmet Karamercan, Mehmet Eren Yuksel, Gamze Kulduk


Pancreatic schwannoma is a rare neoplasm. By 2012, there were only 47 cases reported on pancreatic schwannoma in the English literature to the best of our knowledge. Hereby, we report a 37-year-old Caucasian male with a cystic schwannoma in the head of the pancreas. The patient, complaining of vague abdominal pain and pruritus underwent a computed tomography (CT) scan of the abdomen. The CT scan of the abdomen revealed a cystic lesion in the head of the pancreas. Initially, a cystic mucinous tumor of the pancreas was suspected. Whipple’s procedure was undertaken. The histopathologic evaluation of the specimen revealed a pancreatic schwannoma. The patient did well postoperatively. Even rarely seen, pancreatic schwannoma should be taken into account in the differential diagnosis of pancreatic lesions.


Pancreas; Schwannoma; Whipple

Full Text:



Bai, X. L., Zhang, Q., Masood, N., Masood, W., Zhang, Y., & Liang, T. B. (2013). Pancreatic cystic neoplasms: a review of preoperative diagnosis and management. Journal of Zhejiang University Science B, 14(3), 185-194. doi: 10.1631/jzus.B1200283

Bui, T. D., Nguyen, T., Huerta, S., Gu, M., & Hsiang, D. (2004). Pancreatic schwannoma. A case report and review of the literature. Journal of the Pancreas, 5(6), 520-526.

Di Benedetto, F., Spaggiari, M., De Ruvo, N., Masetti, M., Montalti, R., Quntini, C., Gerunda, G. E. (2007). Pancreatic schwannoma of the body involving the splenic vein: case report and review of the literature. European Journal of Surgical Oncology, 33(7), 926-928. doi: 10.1016/j.ejso.2006.09.011

Gupta, A., Subhas, G., Mittal, V. K., & Jacobs, M. J. (2009). Pancreatic schwannoma: literature review. Journal of Surgical Education, 66(3), 168-173. doi: 10.1016/j.jsurg.2008.12.001

Kinhal, V. A., Ravishankar, T. H., Melapure, A. I., Jayaprakasha, G., Range Gowda, B. C., & Manjunath. (2010). Pancreatic schwannoma: Report of a case and review of literature. Indian Journal of Surgery, 72(Suppl 1), 296-298. doi: 10.1007/s12262-010-0112-6

Kurtkaya-Yapicier, O., Scheithauer, B., & Woodruff, J. M. (2003). The pathobiologic spectrum of Schwannomas. Journal of Histology & Histopathology, 18(3), 925-934.

Lennon, A. M., & Wolfgang, C. (2013). Cystic neoplasms of the pancreas. Journal of Gastrointestinal Surgery, 17(4), 645-653. doi: 10.1007/s11605-012-2072-6

Moriya, T., Kimura, W., Hirai, I., Takeshita, A., Tezuka, K., Watanabe, T., Fuse, A. (2012). Pancreatic schwannoma: Case report and an updated 30-year review of the literature yielding 47 cases. World Journal of Gastroenterology, 18(13), 1538-1544. doi: 10.3748/wjg.v18.i13.1538

Mummadi, R. R., Nealon, W. H., Artifon, E. L., Fleming, J. B., & Bhutani, M. S. (2009). Pancreatic Schwannoma presenting as a cystic lesion. Gastrointestinal Endoscopy, 69(2), 341; discussio 341. doi: 10.1016/j.gie.2008.08.036

Stojanovic, M. P., Radojkovic, M., Jeremic, L. M., Zlatic, A. V., Stanojevic, G. Z., Jovanovic, M. A., Katic, V. P. (2010). Malignant schwannoma of the pancreas involving transversal colon treated with en-bloc resection. World Journal of Gastroenterology, 16(1), 119-122.

Weiss, S. W., Langloss, J. M., & Enzinger, F. M. (1983). Value of S-100 protein in the diagnosis of soft tissue tumors with particular reference to benign and malignant Schwann cell tumors. Laboratory Investigation, 49(3), 299-308.



  • There are currently no refbacks.

Print ISSN 1804-5804, Online ISSN 1804-9702

(c) 2018 CBU,o.p.s.